Gunther Wennemuth
Our lab has a broad spectrum in questions concerning reproductive biology and immunology. We investigate Ion- and proton channels as crucial molecules enabling sperm to regulate all of their key functions like motility, hyperactivation or sperm-egg communication.
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Our Research / Unsere Forschung
Latest publications
Zhao, Y, Wang, H, Wiesehoefer, C, Shah, NB, Reetz, E, Hwang, JY, Huang, X, Wang, TE, Lishko, PV, Davies, KM et al. (2022). 3D structure and in situ arrangements of CatSper channel in the sperm flagellum. Nat Commun13,3439.
Kyrylenko, S, Gogotsi, O, Baginskiy, I, Balitskyi, V, Zahorodna, V, Husak, Y, Yanko, I, Pernakov, M, Roshchupkin, A, Lyndin, M et al. (2022). MXene-Assisted Ablation of Cells with a Pulsed Near-Infrared Laser. ACS Appl Mater Interfaces14,28683-28696.
Zaffran, I, Landolina, N, Gaur, P, Rovis, TL, Stipan, J, Mandelboim, O, Singer, BB, Levi-Schaffer, F (2022). Activation of CEACAM1 with an agonistic monoclonal antibody results in inhibition of melanoma cells. Cancer Gene Ther,.
Wiesehöfer, C, Wiesehöfer, M, Dankert, JT, Chung, JJ, von Ostau, NE, Singer, BB, Wennemuth, G (2022). CatSper and its CaM-like Ca2+ sensor EFCAB9 are necessary for the path chirality of sperm. FASEB J36,e22288.
Walwyn-Brown, K, Pugh, J, Cocker, ATH, Beyzaie, N, Singer, BB, Olive, D, Guethlein, LA, Parham, P, Djaoud, Z (2022). Phosphoantigen-Stimulated γδ T Cells Suppress Natural Killer-Cell Responses to Missing-Self. Cancer Immunol Res10,558-570.
Klaile, E, Prada Salcedo, JP, Klassert, TE, Besemer, M, Bothe, AK, Durotin, A, Müller, MM, Schmitt, V, Luther, CH, Dittrich, M et al. (2022). Antibody ligation of CEACAM1, CEACAM3, and CEACAM6, differentially enhance the cytokine release of human neutrophils in responses to Candida albicans. Cell Immunol371,104459.
Taxauer, K, Hamway, Y, Ralser, A, Dietl, A, Mink, K, Vieth, M, Singer, BB, Gerhard, M, Mejías-Luque, R (2021). Engagement of CEACAM1 by Helicobacterpylori HopQ Is Important for the Activation of Non-Canonical NF-κB in Gastric Epithelial Cells. Microorganisms9,.
Galaski, J, Shhadeh, A, Umaña, A, Yoo, CC, Arpinati, L, Isaacson, B, Berhani, O, Singer, BB, Slade, DJ, Bachrach, G et al. (2021). Fusobacterium nucleatum CbpF Mediates Inhibition of T Cell Function Through CEACAM1 Activation. Front Cell Infect Microbiol11,692544.
Turner, MA, Amirfakhri, S, Nishino, H, Lwin, TM, Savides, TJ, Reid, TR, Singer, BB, Hoffman, RM, Bouvet, M . A Patient-Derived Orthotopic Xenograft Model of Gastroesophageal-Junction Adenocarcinoma Translated to the Clinic by Tumor-Targeting Fluorescent Antibodies to Carcinoembryonic-Antigen-Related Cell-Adhesion Molecules. In Vivo35,1959-1963.
Kube, I, Jastrow, H, Führer, D, Zwanziger, D (2021). Thyroid Hormone Deficiency Modifies Hepatic Lipid Droplet Morphology and Molecular Properties in Lithogenic-Diet Supplemented Mice. Exp Clin Endocrinol Diabetes129,926-930.
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